PULMICORT FLEXHALER
ICS DPI
Budesonide · AstraZeneca
Active Medication & Mechanism
- Budesonide ICS90 mcg or 180 mcg per actuation (delivers approximately 80 mcg or 160 mcg from the mouthpiece)
Corticosteroid with potent glucocorticoid and weak mineralocorticoid activity. Reduces airway inflammation by inhibiting inflammatory cell recruitment and cytokine production.
FDA-Approved Dosing by Indication
// approval varies by strength + age Asthma
3/4 approved regimens| Strength | Population | Dose & Frequency | Total Daily | Status |
|---|---|---|---|---|
| 180 mcg | Adults and adolescents ≥18 years (previously on bronchodilators alone) | 2 inhalations (360 mcg) twice daily Starting dose. Maximum dose is 720 mcg twice daily (1440 mcg/day). | 720 mcg | FDA Approved |
| 180 mcg | Adults (previously on ICS) | 2 inhalations (360 mcg) twice daily Starting dose for step-across from another ICS. | 720 mcg | FDA Approved |
| 180 mcg | Adults (previously on oral corticosteroids) | 2–4 inhalations twice daily For oral steroid taper. Max 1440 mcg/day. | 720–1440 mcg | FDA Approved |
| Any strength | Acute bronchospasm | — | — | Not Approved Not a bronchodilator. Not for acute relief. Use a SABA. |
Acute Use
0/1 approved regimens| Strength | Population | Dose & Frequency | Total Daily | Status |
|---|---|---|---|---|
| Any strength | Acute bronchospasm / rescue | — | — | Not Approved Not for acute use. Use a SABA. |